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Orlistat is a powerful medication meant for people who are overweight or obese.
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There have been rare postmarketing reports of severe liver injury with hepatocellular necrosis or acute hepatic failure in patients treated with XENICALwith some of these cases resulting in liver transplant or deathPatients should be instructed to report any symptoms of hepatic dysfunctionanorexiapruritusjaundicedark urinelight-colored stoolsor right upper quadrant painwhile taking XENICALWhen these symptoms occurXENICAL and other suspect medications should be discontinued immediately and liver function tests and ALT and AST levels obtained.
Orlistat blocks your body’s absorption of some fat-soluble vitamins and beta caroteneThereforewhen you use orlistat you should take a daily multivitamin that contains vitamins ADEKand beta-caroteneRead the label to find a multivitamin product that contains these vitaminsTake the multivitamin once a day2 hours before or 2 hours after taking orlistator take the multivitamin at bedtimeAsk your doctor or pharmacist any questions you might have about taking a multivitamin while you are taking orlistat.
Xenical is the prescription-strength form of orlistatThe alli brand is available without a prescription.
If you also take levothyroxinesuch as Synthroiddo not take it within 4 hours before or 4 hours after you take orlistat.
Ethanol does not affect orlistat’s effect on preventing the absorption of fat.
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in 12 normal-weight subjects receiving orlistat 80 mg three times a day for 5 days, orlistat did not alter the pharmacokinetics or pharmacodynamics blood glucose-lowering of glyburide.